Xanthine Oxidase (XDH) Guinea Pig Polyclonal Antibody

CAT#: AP09533SU-N

Xanthine Oxidase (XDH) guinea pig polyclonal antibody, Serum


USD 375.00

2 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western BLot: 1/2000 (ECL).
Immunohistochemistry on Frozen Sections: 1/100-1/200.
Immunohistochemistry on Paraffin Sections:
1/100-1/200 (Microwave treatment required).
Incubation Time: 1 h at RT for immunohistochemistry.
Reactivities Bovine, Human, Mouse, Rat
Host Guinea Pig
Clonality Polyclonal
Immunogen Xanthine Oxidase purified from Bovine Milk Fat Globule Membrane (MFGM).
Specificity The antiserum reacts specifically with Xanthine Oxidase, a 150 kD polypeptide present in lactating mammary gland epithelium and in MFGM. No cross-reaction with other MFGM proteins.
Formulation State: Serum
State: Liquid Serum
Preservative: 0.09% Sodium Azide
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens xanthine dehydrogenase (XDH)
Background In normal tissues this enzyme exists predominantly as Xanthine Dehydrogenase which converts hypoxanthine and xanthine to uric acid, a critical plasma antioxidant. During ischemia, Xanthine Dehydrogenase is reversibly converted to the oxygen radical-producing Xanthine Oxidase by oxidation of essential sulfhydryl groups, or irreversibly, through limited proteolytic cleavage of the amino-terminus. Aldehyde Oxidase has a higher affinity for aldehydes than purines, but produces O2- in a manner very similar to Xanthine Oxidase because both oxidases possess nearly identical internal electron transport systems. 
Xanthine oxidase 150 kD polypeptide is present in the apical membrane of lactating mammary epithelium and in MFGM.
Synonyms Xanthine dehydrogenase/oxidase
Reference Data
Protein Families Druggable Genome
Protein Pathways Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.