VIP Guinea Pig Polyclonal Antibody

CAT#: AP09566SU-N

VIP guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunofluorescence: 1/1000-1/2000 with overnight incubation at 2-8°C.
  Immunohistochemistry on Frozen and Paraffin Sections.
  Recommended Positive Control: Stefanini-fixed frozen sections of rat intestine.
• Reactivities: Feline, Guinea Pig, Human, Porcine, Rabbit, Rat
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: Synthetic Human VIP (Peninsula, #7161).
• Specificity: Antibody AP09566SU-N recognizes VIP (Vasoactive intestinal peptide).
  Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining, while PHI does not.
• Formulation: State: Serum
  State: Lyophilized undiluted serum containing 0.09% sodium azide.
• Reconstitution Method: Dissolve the antiserum in 50-100 µl distilled water,
  and dilute further in 0.1 M PBS with 1% BSA and 0.1% Sodium Azide.
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens vasoactive intestinal peptide (VIP), transcript variant 1
• Database Link:
  Entrez Gene 117064 RatEntrez Gene 7432 Human
• Background: VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP-producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
• Synonyms: VIP, Vasoactive intestinal peptide

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane