MAD3 (MXD3) (C-term) Goat Polyclonal Antibody

CAT#: AP10055PU-N

MAD3 (MXD3) (C-term) goat polyclonal antibody, Aff - Purified


USD 375.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications ELISA, IF, IHC
Recommended Dilution Peptide ELISA: 1/4000 (Detection Limit). 
Western blot: No signal obtained yet but low background observed in NCI-H460, HepG2, Human Liver, Human Heart and Human Brain lysates at up to 3 µg/ml. 
Immunocytochemistry: This product has been successfully used by an anonymous Customer on Methanol-fixed and 0.5% TX100-permeabilized HeLa cells, staning the cytoplasm. 
Immunohistochemistry: An anonymous Customer found positive results on Human HeLa cells.
Reactivities Human
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from the C-Terminus of Human MAD3 (NP_112590.1)
Specificity
This antibody is expected to recognise isoform a (NP_112590.1) only.
Formulation Tris saline, pH~7.3
State: Aff - Purified
State: Liquid purified Ig fraction
Stabilizer: 0.5% BSA
Preservative: 0.02% Sodium Azide
Concentration 0.5 mg/ml
Purification Immunoaffinity Chromatography
Gene Name Homo sapiens MAX dimerization protein 3 (MXD3), transcript variant 2
Background MAD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Synonyms MAD-3, MXD3,Max-interacting transcriptional repressor MAD3
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.