GABA A Receptor beta 3 (GABRB3) Goat Polyclonal Antibody

CAT#: AP10064PU-N

GABA A Receptor beta 3 (GABRB3) goat polyclonal antibody, Aff - Purified


USD 375.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution Peptide ELISA: 1/8000.
Immunohistochemistry on paraffin sections: Human Cortex shows patchy staining near or at the neuronal cell membrane.
Recommended concentration: 2-4µg/ml.
Reactivities Bovine, Canine, Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-EKTAKAKNDRSK, from the internal region of the protein sequence according to NP_000805.1; NP_068712.1.
Specificity This antibody reacts to GABRB3.
Formulation Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens gamma-aminobutyric acid type A receptor beta3 subunit (GABRB3), transcript variant 1
Background GABA A Receptor beta 3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system.
The GABAA receptor complex is the molecular target of the benzodiazepine class of tranquilizer drugs, and hence it is also often referred to as the 'benzodiazepine receptor'. The GABAA receptor complex also appears to have distinct binding sites for a variety of other pharmaco-active compounds.
Synonyms GABRB-3, GABA A receptor subunit beta-3
Reference Data
Protein Families Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction

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