JMJD6 (N-term) Rabbit Polyclonal Antibody

CAT#: AP11061PU-N

JMJD6 (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-PTDSR (N-term) Pab in mouse heart, Hela, and HL60 cell line lysates. PTDSR (N-term) (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/250-1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PTDSR.
• Specificity: This antibody is specific to PTDSR (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens arginine demethylase and lysine hydroxylase (JMJD6), transcript variant 1
• Database Link:
  Entrez Gene 107817 MouseEntrez Gene 23210 Human
• Background: Also known as JmjC domain-containing protein 6. This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. It functions in differentiation of multiple tissues during development, and in anti-inflammatory cytokine signaling. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have suggested that the protein may cross-react with a monoclonal antibody that recognizes the phosphatidylserine receptor and does not directly function in the clearance of apoptotic cells.
• Synonyms: KIAA0585, Phosphatidylserine receptor

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS