HTRA1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP11327PU-N

HTRA1 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis using anti-HtrA1 (C-term) Pab to detect HtrA1 in placenta tissue lysate.

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  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389~419 amino acids from the C-terminal region of Human HtrA1.
• Specificity: This antibody is specific to HTRA1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: HtrA serine peptidase 1
• Database Link:
  Entrez Gene 5654 Human
  UniProt ID Q92743
• Background: HtrA1 is a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.
• Synonyms: HTRA, L56, Serine protease 11
• Note: Calculated Molecular Weight: 51286 Da