SLUG (SNAI2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP11931PU-N

SLUG (SNAI2) (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-SLUG Antibody (N-term) in A2058 cell line lysates (35 ug/lane). SLUG (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/1,000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human SLUG.
• Specificity: This antibody detects SLUG at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: snail family transcriptional repressor 2
• Database Link:
  Entrez Gene 6591 Human
• Background: SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.
• Synonyms: SLUGH
• Note: Molecular weight: 29986 Da