GDF1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP11940PU-N

GDF1 (N-term) rabbit polyclonal antibody, Purified

Product Images

The anti-GDF1 N-term is used in Western blot to detect GDF1 in A375 cell lysate.

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA 1:1,000.
  Western blot 1:100 - 1:500.
  Immunohistochemistry 1:10 - 1:50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF1.
• Specificity: This antibody detects GDF1 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens growth differentiation factor 1 (GDF1)
• Database Link:
  Entrez Gene 2657 Human
• Background: GDF1 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right assymetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA which also encodes the longevity assurance gene.
• Synonyms: Embryonic growth/differentiation factor 1, GDF-1
• Note: Molecular weight: 39502 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein