Serine Palmitoyltransferase (SPTLC2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP12257PU-N

Serine Palmitoyltransferase (SPTLC2) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-SPTLC2 (C-term) Pab to detect SPTLC2 in mouse liver tissue lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: ~1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 531-562 amino acids from the C-terminal region of human Serine Palmitoyltransferase (SPTLC2).
• Specificity: This antibody is specific to SPTLC2 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: serine palmitoyltransferase long chain base subunit 2
• Database Link:
  Entrez Gene 9517 Human
• Background: Serine palmitoyltransferase (SPT) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.
  The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate.
• Synonyms: Serine palmitoyltransferase 2, SPT 2, SPT2, LCB 2, LCB2, LCB2a, KIAA0526
• Note: Predicted Molecular weight: 62924 Da