SULT2B1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP12292PU-N

SULT2B1 (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of SULT2B1a/b antibody (N-term) (Cat.#AP12292PU-N) in HL60 cell line lysates (35ug/lane). SULT2B1a/b (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SULT2B1a/b.
• Specificity: This antibody detects SULT2B1a/b (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens sulfotransferase family 2B member 1 (SULT2B1), transcript variant 1
• Database Link:
  Entrez Gene 6820 Human
• Background: Cytosolic sulfotransferases (STs or SULTs) catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. Her et al. (1998) identified an EST with homology to ST enzymes. By PCR with human placental and prostate cDNA as template, they isolated 2 alternatively spliced cDNAs, identical throughout most of their sequences, but having different 5-prime ends. The shorter cDNA, SULT2B1a, encodes a protein of 350 amino acids; the longer cDNA, SULT2B1b, encodes a 365-amino acid protein. Genomic PCR analysis revealed that the gene encoding both cDNAs, SULT2B1, contains 7 exons, with 2 alternative first exons being used to generate SULT2B1a and SULT2B1b. Northern blot analysis revealed that the SULT2B1 gene is expressed as a 1.4-kb transcript predominantly in prostate, placenta, and trachea.
• Synonyms: Sulfotransferase 2B1, ST2B1, Alcohol sulfotransferase, HSST2
• Note: Molecular weight: 41307 Da and 39599 Da

Reference Data

• Protein Pathways: Androgen and estrogen metabolism, Sulfur metabolism