MAGEA2 (MAGEA2B) (N-term) Rabbit Polyclonal Antibody

CAT#: AP13129PU-N

MAGEA2 (MAGEA2B) (N-term) rabbit polyclonal antibody, Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Immunohistochemistry: 1/50 - 1/100.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MAGEA2.
Specificity This antibody reacts to MAGEA2.
Formulation PBS with 0.09% (W/V) sodium azide
State: Purified
State: Liquid purified Ig
Concentration lot specific
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name MAGE family member A2B
Background MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.
Synonyms Melanoma-associated antigen 2, MAGEA2, MAGE2, MAGEA2A, MAGE 2
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.