Sclerostin (SOST) (N-term) Rabbit Polyclonal Antibody

CAT#: AP13235PU-N

Sclerostin (SOST) (N-term) rabbit polyclonal antibody, Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/1,000.
Immunohistochemistry: 1/10-1/50.
Reactivities Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of Human SOST.
Specificity This antibody recognizes SOST.
Formulation PBS
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.09% (W/V) Sodium Azide
Concentration lot specific
Purification Protein A column, followed by peptide affinity purification
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name sclerostin
Background Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Synonyms sclerosteosis; sclerostin; VBCH
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.