RET (N-term) Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/1,000. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 152-182 amino acids from the N-terminal region of Human RET. |
Specificity | This antibody recognizes Human RET. Other species not tested. |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 124319 Da |
Gene Name | ret proto-oncogene |
Database Link | |
Background | RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. |
Synonyms | C-ret, CDHF12 |
Reference Data |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.