alpha Actinin (ACTN1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17086PU-N

alpha Actinin (ACTN1) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of ACTN1 Antibody (N-term) in MDA-MB231 cell line lysates (35 ug/lane). ACTN1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:100 - 1:500.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human ACTN1
• Specificity: This antibody detects Alpha-actinin-1 / ACTN1 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column, followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens actinin alpha 1 (ACTN1), transcript variant 2
• Database Link:
  Entrez Gene 87 Human
• Background: ACTN1 is a F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
• Synonyms: Alpha actinin cytoskeletal isoform, Non-muscle alpha-actinin 1
• Note: Molecular weight: 103058 Da

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Systemic lupus erythematosus, Tight junction