Caldesmon (CALD1) Rabbit Polyclonal Antibody
Other products for "CALD1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1:50 - 1:100. ELISA: 1:1,000. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from the Center region of human CALD1 |
Specificity | This antibody detects Caldesmon at Center. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens caldesmon 1 (CALD1), transcript variant 2 |
Database Link | |
Background | CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. |
Synonyms | CALD1, CAD, CDM |
Note | Molecular weight: 93250 Da |
Reference Data | |
Protein Pathways | Vascular smooth muscle contraction |
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