Caldesmon (CALD1) Rabbit Polyclonal Antibody

CAT#: AP17164PU-N

Caldesmon (CALD1) rabbit polyclonal antibody

Product Images

Western blot analysis of CALD1 antibody (Center) in A2058 cell line lysates (35 ug/lane). CALD1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CALD1
• Specificity: This antibody detects Caldesmon at Center.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: caldesmon 1
• Database Link:
  Entrez Gene 800 Human
  UniProt ID Q05682
• Background: CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.
• Synonyms: CALD1, CAD, CDM
• Note: Molecular weight: 93250 Da

Reference Data

• Protein Pathways: Vascular smooth muscle contraction