Collagen VI (COL6A1) alpha 1 chain Rabbit Polyclonal Antibody

CAT#: AP17225PU-N

Collagen VI (COL6A1) alpha 1 chain rabbit polyclonal antibody

Product Images

Western blot analysis of COL6A1 antibody (C-term) in Y79 cell line lysates (35 ug/lane). COL6A1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human COL6A1
• Specificity: This antibody detects COL6A1 at C-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: collagen type VI alpha 1
• Database Link:
  Entrez Gene 1291 Human
  UniProt ID P12109
• Background: The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
• Synonyms: COL6A1
• Note: Molecular weight: 108529 Da

Reference Data

• Protein Pathways: ECM-receptor interaction, Focal adhesion