COMP (Center) Rabbit Polyclonal Antibody
Other products for "COMP"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1:100 - 1:500. ELISA: 1:1,000. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from the Center region of human COMP |
Specificity | This antibody detects COMP at Center. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Purified through a protein A column, followed by peptide affinity purification |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens cartilage oligomeric matrix protein (COMP) |
Database Link | |
Background | COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. |
Synonyms | Cartilage oligomeric matrix protein |
Note | Molecular weight: 82860 Da |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway |
Documents
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