Cathepsin K (CTSK) Rabbit Polyclonal Antibody

CAT#: AP17260PU-N

Cathepsin K (CTSK) rabbit polyclonal antibody, Aff - Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications FC, IHC, WB
Recommended Dilution Western blot: 1:1000.
Immunohistochemistry on formalin-fixed, paraffin-embedded sections: 1:10 - 1:50.
Flow Cytometry: 1:10 - 1:50.
Reactivities Bovine, Human, Monkey, Porcine, Rabbit
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between aa 207-27 from the Center region of human CTSK.
Specificity This antibody detects Cathepsin K at Center.
Formulation PBS with 0.09% (W/V) sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Purified through Protein A column followed by peptide affinity purification.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens cathepsin K (CTSK)
Background The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Synonyms Cathepsin O, Cathepsin X, Cathepsin O2, CTSK, CTSO, CTSO2
Note Molecular weight: 36966 Da
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Lysosome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.