Dermcidin (DCD) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17270PU-N

Dermcidin (DCD) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of DCD antibody (C-term) in T47D cell line lysates (35 ug/lane). DCD (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human DCD
• Specificity: This antibody detects DCD at C-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens dermcidin (DCD), transcript variant 1
• Database Link:
  Entrez Gene 117159 Human
• Background: DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
• Synonyms: DCD, AIDD, DSEP, Preproteolysin
• Note: Molecular weight: 11284 Da

Reference Data

• Protein Families: Secreted Protein