Fibrinogen beta chain (FGB) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17373PU-N

Fibrinogen beta chain (FGB) (C-term) rabbit polyclonal antibody


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Specifications

Product Data
Applications WB
Recommended Dilution Western blot: 1:50 - 1:100.
ELISA: 1:1,000.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human FIBB
Specificity This antibody detects FIBB at C-term.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid Ig fraction
Concentration lot specific
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens fibrinogen beta chain (FGB), transcript variant 1
Background FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Synonyms FGB, FIBB
Note Molecular weight: 55928 Da
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.