Folylpolyglutamate synthase (FPGS) Rabbit Polyclonal Antibody

CAT#: AP17399PU-N

Folylpolyglutamate synthase (FPGS) rabbit polyclonal antibody

Product Images

Western blot analysis of FPGS Antibody (Center) in K562, A2058 cell line lysates (35 ug/lane). FPGS (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:100 - 1:500.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human FPGS
• Specificity: This antibody detects FPGS at Center.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column, followed by peptide affinity purification
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens folylpolyglutamate synthase (FPGS), transcript variant 2
• Database Link:
  Entrez Gene 2356 Human
• Background: FPGS is the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives.
• Synonyms: Folylpolyglutamate synthase, Tetrahydrofolate synthase
• Note: Molecular weight: 64609 Da

Reference Data

• Protein Pathways: Folate biosynthesis, Metabolic pathways