GALE (Center) Rabbit Polyclonal Antibody

CAT#: AP17410PU-N

GALE (Center) rabbit polyclonal antibody

Product Images

Western blot analysis of GALE Antibody (Center) in A375 cell line lysates (35 ug/lane). GALE (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:100 - 1:500.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human GALE
• Specificity: This antibody detects GALE at Center.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column, followed by peptide affinity purification
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens UDP-galactose-4-epimerase (GALE), transcript variant 1
• Database Link:
  Entrez Gene 2582 Human
• Background: UDP-galactose-4-epimerase catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids.
• Synonyms: Galactowaldenase, UDP-glucose 4-epimerase, UDP-galactose 4-epimerase
• Note: Molecular weight: 38282 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways