Galactosidase alpha (GLA) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17424PU-N

Galactosidase alpha (GLA) (N-term) rabbit polyclonal antibody


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western blot: 1/50 - 1/100.
ELISA: 1/1,000.
Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 90~120 amino acids from the N-terminal region of human GLA
Specificity This antibody detects GLA at N-term.
Formulation PBS with 0.09% (W/V) sodium azide as preservative
State: Liquid purified Ig fraction
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens galactosidase alpha (GLA)
Background GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Synonyms Alpha-D-galactosidase A, Melibiase
Note Molecular weight: 48767 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo series, Lysosome, Sphingolipid metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.