HFE (Center) Rabbit Polyclonal Antibody

CAT#: AP17460PU-N

HFE (Center) rabbit polyclonal antibody

Product Images

Western blot analysis of HFE antibody (Center) in Jurkat cell line lysates (35 ug/lane). HFE (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human HFE
• Specificity: This antibody detects HFE at Center.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens hemochromatosis (HFE), transcript variant 1
• Database Link:
  Entrez Gene 3077 Human
• Background: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
• Synonyms: dJ221C16.10.1; hemochromatosis; HFE1; HH; HLA-H; HLAH; MGC103790; MVCD7
• Note: Molecular weight: 40108 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane