HOMER3 Rabbit Polyclonal Antibody

CAT#: AP17478PU-N

HOMER3 rabbit polyclonal antibody

Product Images

(LEFT) Western blot analysis of HOMER3 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane).HOMER3 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of HOMER3 Antibody (Center) in NIH-3T3 cell line lysates (35ug/lane).HOMER3 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human HOMER3
• Specificity: This antibody reacts to HOMER3.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens homer scaffolding protein 3 (HOMER3), transcript variant 2
• Database Link:
  Entrez Gene 26558 MouseEntrez Gene 9454 Human
• Background: HOMER3 is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. This protein binds numerous other proteins including group I metabotropic glutamate receptors,inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides.
• Synonyms: Homer protein homolog 3, Homer-3

Reference Data

• Protein Families: Druggable Genome