Kir2.1 (KCNJ2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17516PU-N

Kir2.1 (KCNJ2) (C-term) rabbit polyclonal antibody

Product Images

(LEFT) Western blot analysis of KCNJ2 Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of KCNJ2 Antibody (C-term) in mouse lung tissue lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human KCNJ2
• Specificity: This antibody reacts to KCNJ2.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens potassium voltage-gated channel subfamily J member 2 (KCNJ2)
• Database Link:
  Entrez Gene 16518 MouseEntrez Gene 3759 Human
• Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. This protein is an integral membrane protein and inward-rectifier type potassium channel. This protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is racterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
• Synonyms: KCNJ2, HIRK1, Inward rectifier K(+) channel Kir2.1, Cardiac inward rectifier potassium channel, IRK1, Inward rectifier potassium channel 2

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane