P4HB (C-term) Rabbit Polyclonal Antibody

CAT#: AP17615PU-N

P4HB (C-term) rabbit polyclonal antibody


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications FC, IHC, WB
Recommended Dilution ELISA: >1/1,000 (peptide ELISA only)
Western blotting: 1/500-1/1000.
Flow Cytometry: 1/10-1/50.
Immunohistochemistry: 1/50-1/100.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 436~464 amino acids from the C-terminal region of Human P4HB.
Specificity This antibody recognizes Protein Disulfide Isomerase.
Formulation PBS with 0.09% (W/V) Sodium Azide as preservative
State: Liquid purified Ig fraction
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB)
Background P4HB is a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
Synonyms ERBA2L, PDIA1, PO4DB, Protein disulfide-isomerase, ER marker
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.