PABP (PABPC1) (Center) Rabbit Polyclonal Antibody

CAT#: AP17616PU-N

PABP (PABPC1) (Center) rabbit polyclonal antibody


USD 450.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the Center region of human PABPC1
Specificity This antibody reacts to PABPC1.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens poly(A) binding protein cytoplasmic 1 (PABPC1)
Background PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Synonyms PAB1, PABP-1, PABP1, Polyadenylate-binding protein 1, PABPC2
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.