eNOS (NOS3) pSer1177 Rabbit Polyclonal Antibody

CAT#: AP17636PU-N

eNOS (NOS3) pSer1177 rabbit polyclonal antibody

Product Images

Dot blot analysis of anti-Phospho-eNos-S1177 Phospho-specific Pab (AP17636PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Specifications

Product Data

• Recommended Dilution: ELISA: 1/1,000.
  Dot blot: 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1177 of human eNos
• Specificity: This antibody reacts to Ser1177 phosphorylated NOS3.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens nitric oxide synthase 3 (NOS3), transcript variant 1
• Database Link:
  Entrez Gene 4846 Human
• Background: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases.
• Synonyms: Endothelial NOS, EC-NOS, NOS type III, Constitutive NOS, eNOS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Arginine and proline metabolism, Calcium signaling pathway, Long-term depression, Metabolic pathways, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway