CD130 (IL6ST) pTyr905 Rabbit Polyclonal Antibody

CAT#: AP17638PU-N

CD130 (IL6ST) pTyr905 rabbit polyclonal antibody

Product Images

Dot blot analysis of anti-Phospho-IL6ST-Y905 Phospho-specific Pab (AP17638PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Specifications

Product Data

• Recommended Dilution: Peptide ELISA: 1/1,000.
  Dot blot: 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y905 of Human IL6ST
• Specificity: This antiobdy reacts to Tyr905 phosphorylated CD130 / IL6ST.
• Formulation: PBS
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 6 signal transducer (IL6ST), transcript variant 1
• Database Link:
  Entrez Gene 3572 Human
• Background: IL6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein.
• Synonyms: Interleukin-6 receptor subunit beta, IL-6R-beta, IL6 receptor beta

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway