Plzf (ZBTB16) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17652PU-N

Plzf (ZBTB16) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of PLZF antibody (C-term) in K562 cell line lysates (35ug/lane). PLZF (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human PLZF
• Specificity: This antibody reacts to ZBTB16.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purfied Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens zinc finger and BTB domain containing 16 (ZBTB16), transcript variant 2
• Database Link:
  Entrez Gene 7704 Human
• Background: PLZF is a member of the Krueppel C2H2-type zinc-finger protein family and a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL).
• Synonyms: PLZF, ZNF145

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Pathways in cancer