Cyclophilin A (PPIA) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17657PU-N

Cyclophilin A (PPIA) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of PPIA Antibody (N-term) in T47D cell line and mouse brain, bladder tissue lysates (35ug/lane). PPIA (arrow) was detected using the purified Pab. (2ug/ml)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human PPIA
• Specificity: This antibody reacts to Cyclophilin A.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens peptidylprolyl isomerase A (PPIA), transcript variant 1
• Database Link:
  Entrez Gene 268373 MouseEntrez Gene 5478 Human
• Background: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.
• Synonyms: PPIA, CYPA, Cyclosporin A-binding protein, Cyclophilin-A, Peptidyl-prolyl cis-trans isomerase A, PPIase A, Rotamase A, EC=5.2.1.8