RRM2 (Center) Rabbit Polyclonal Antibody

CAT#: AP17721PU-N

RRM2 (Center) rabbit polyclonal antibody

Product Images

Western blot analysis of RRM2 antibody (Center) in Jurkat cell line lysates (35ug/lane). RRM2 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human RRM2
• Specificity: This antibody reacts to RRM2.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ribonucleotide reductase regulatory subunit M2 (RRM2), transcript variant 2
• Database Link:
  Entrez Gene 6241 Human
• Background: RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
• Synonyms: Ribonucleotide reductase small subunit, Ribonucleotide reductase small chain

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism