RYK (Center) Rabbit Polyclonal Antibody

CAT#: AP17727PU-N

RYK (Center) rabbit polyclonal antibody

Product Images

Western blot analysis of RYK antibody (Center C397) in Hela cell line lysates (35ug/lane). RYK (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human RYK
• Specificity: This antibody reacts to Tyrosine-protein kinase RYK.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens receptor-like tyrosine kinase (RYK), transcript variant 1
• Database Link:
  Entrez Gene 6259 Human
• Background: RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
• Synonyms: JTK5A

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane