SF2 (SRSF1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17742PU-N

SF2 (SRSF1) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of SFRS1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). SFRS1 (arrow) was detected using the purified Pab.

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  Formalin-Fixed, Paraffin-Embedded Human colon carcinoma reacted with SFRS1 Antibody (C-term), which was Peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50-1/100.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 165~194 amino acids from the C-terminal region of Human SFRS1
• Specificity: This antibody recognizes SFRS1.
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: serine/arginine-rich splicing factor 1
• Database Link:
  Entrez Gene 6426 Human
  UniProt ID Q07955
• Background: SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.
• Synonyms: ASF, ASF-1, Alternative-splicing factor 1, SF2P33

Reference Data

• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Spliceosome