Prealbumin (TTR) (Center) Rabbit Polyclonal Antibody

CAT#: AP17811PU-N

Prealbumin (TTR) (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of TTR Antibody (Center) in HepG2 cell line lysates (35ug/lane). TTR (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: Peptide ELISA: 1/1,000.
  Western blotting: 1/1,000.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human, Bovine
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 47-74 amino acids from the Central region of human TTR.
• Specificity: This antibody reacts to Transthyretin.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transthyretin
• Database Link:
  Entrez Gene 7276 Human
  UniProt ID P02766
• Background: Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
• Synonyms: TTR, ATTR, TBPA, PALP

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Secreted Protein