CRM1 (XPO1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17839PU-N

CRM1 (XPO1) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of XPO1 antibody (C-term) in mouse bladder tissue lysates (35ug/lane). XPO1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human XPO1
• Specificity: This antibody reacts to Exportin-1.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: exportin 1
• Database Link:
  Entrez Gene 103573 MouseEntrez Gene 7514 Human
  UniProt ID O14980
• Background: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
• Synonyms: Exp1, CRM1

Reference Data

• Protein Families: Druggable Genome