ARSB (Center) Rabbit Polyclonal Antibody

CAT#: AP17890PU-N

ARSB (Center) rabbit polyclonal antibody

Product Images

(LEFT) Western blot analysis of ARSB Antibody (Center) in HL-60 cell line lysates (35ug/lane).ARSB (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of ARSB (arrow) using rabbit polyclonal ARSB Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ARSB gene (Lane 2) (Origene Technologies).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human ARSB
• Specificity: This antibody reacts to Arylsulfatase B.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens arylsulfatase B (ARSB), transcript variant 1
• Database Link:
  Entrez Gene 411 Human
• Background: ARSB belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B.
• Synonyms: ASB, ARSB, G4S

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycosaminoglycan degradation, Lysosome, Metabolic pathways