BDKRB1 (Center) Rabbit Polyclonal Antibody

CAT#: AP17901PU-N

BDKRB1 (Center) rabbit polyclonal antibody

Product Images

Western blot analysis of BDKRB1 Antibody (Center) in HepG2 cell line lysates (35ug/lane). BDKRB1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human BDKRB1
• Specificity: This antibody reacts to BDKRB1.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens bradykinin receptor B1 (BDKRB1)
• Database Link:
  Entrez Gene 623 Human
• Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
• Synonyms: BRADYB1, BKB1R, BKR1, B1 bradykinin receptor, Bradykinin B1 Receptor, BK-1 receptor, B1R

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton