CARD4 (NOD1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17920PU-N

CARD4 (NOD1) (C-term) rabbit polyclonal antibody, Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Other products for "NOD1"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/100-1/500.
Immunohistochemistry: 1/50-1/100.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of Human CARD4.
Specificity This antibody recognizes CARD4 / NOD1 (C-term).
Formulation PBS with 0.09% (W/V) Sodium Azide as preservative.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Affinity Chromatography on Protein A.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens nucleotide binding oligomerization domain containing 1 (NOD1)
Background CARD4 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
Synonyms CARD4; CLR7.1; NLRC1
Note Calculated Molecular Weight: 107691 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.