CEBP Beta (CEBPB) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17939PU-N

CEBP Beta (CEBPB) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of CEBPB (arrow) using rabbit polyclonal CEBPB Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CEBPB gene (Lane 2).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human CEBPB
• Specificity: This antibody reacts to CEBPB.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens CCAAT/enhancer binding protein beta (CEBPB), transcript variant 1
• Database Link:
  Entrez Gene 1051 Human
• Background: CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
• Synonyms: C/EBP beta, TCF5, LAP, NF-IL6

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors