Cytochrome p450 2J2 (CYP2J2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17970PU-N

Cytochrome p450 2J2 (CYP2J2) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of CYP2J2 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). CYP2J2 (arrow) was detected using the purified Pab.

• 

  Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP2J2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human CYP2J2
• Specificity: This antibody reacts to CYP2J2.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens cytochrome P450 family 2 subfamily J member 2 (CYP2J2), transcript variant 1
• Database Link:
  Entrez Gene 1573 Human
• Background: CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.
• Synonyms: Cytochrome P450 2J2, CYPIIJ2

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Arachidonic acid metabolism, Linoleic acid metabolism, Metabolic pathways