PTGIS (C-term) Rabbit Polyclonal Antibody

CAT#: AP17980PU-N

PTGIS (C-term) rabbit polyclonal antibody, Purified


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Other products for "PTGIS"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/1,000.
Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of Human CYP8A1.
Specificity This antibody recognizes PTGIS.
Formulation PBS
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.09% (W/V) Sodium Azide
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Predicted Protein Size 57104 kDa
Gene Name Homo sapiens prostaglandin I2 synthase (PTGIS)
Background CYP8A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
Synonyms Prostacyclin Synthase, CYP8, CYP8A1
Reference Data
Protein Families Druggable Genome, P450, Transmembrane
Protein Pathways Arachidonic acid metabolism, Metabolic pathways

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.