Superoxide Dismutase 1 (SOD1) (Center) Rabbit Polyclonal Antibody

CAT#: AP18205PU-N

Superoxide Dismutase 1 (SOD1) (Center) rabbit polyclonal antibody

Product Images

Western blot analysis of SOD1 Antibody (Center) in Jurkat cell line lysates (35ug/lane). SOD1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human SOD1
• Specificity: This antibody reacts to Superoxide Dismutase 1 (SOD1).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: superoxide dismutase 1, soluble
• Database Link:
  Entrez Gene 6647 Human
  UniProt ID P00441
• Background: SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.
• Synonyms: SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases