XPA (C-term) Rabbit Polyclonal Antibody

CAT#: AP18245PU-N

XPA (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of XPA Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). XPA (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: conjugated synthetic peptide selected from the C-term region of human XPA
• Specificity: This antibody reacts to XPAC.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant 1
• Database Link:
  Entrez Gene 7507 Human
• Background: XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
• Synonyms: XP1; XPAC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair