Lamin B1 (LMNB1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP20052PU-N

Lamin B1 (LMNB1) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot: Lamin B1 antibody staining of Ramos cell line lysates (35 ug/lane). Lamin B1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000
  Western blotting: ~1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of Human Lamin B1.
• Specificity: Recognizes Lamin B1 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens lamin B1 (LMNB1), transcript variant 1
• Database Link:
  Entrez Gene 4001 Human
• Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.
• Synonyms: Lamin-B1, LMNB1, LMNB-1, LMN2, LMNB, Nuclear Envelope Marker