EPHX2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP20088PU-N

EPHX2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry: EPHX2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Heart.

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  Immunohistochemistry: EPHX2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Placenta.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 - 10 µg/ml.
• Reactivities: Human, Monkey
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic 17 amino acid peptide from C-Terminus of human EPHX2
• Specificity: Reacts with C-Terminus of Soluble Epoxide Hydrolase (EPHX2).
• Formulation: PBS containing 0.09% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens epoxide hydrolase 2 (EPHX2), transcript variant 1
• Database Link:
  Entrez Gene 2053 Human
• Background: Soluble Epoxide Hydrolase (sEH) also known as cytosolic Epoxide Hydrolase is a phase I xenobiotic-metabolizing enzyme that converts epoxyeicosatrienoic acids (EETs) into their corresponding dihydroxyeicosatrienoic acids (DHETs). EETs are thought to be involved in vascular tone, ion channel regulation, mitogenesis and cell signaling. DHETs have, in general, less biological activity then EETs and are more readily excreted, thus hydration of EETs by sEH maybe a means of attenuating or eliminating their activity.
  sEHs have been identified in many tissues including liver, kidney, adrenal, pancreatic islets, gi tract and vascular smooth muscle.
• Synonyms: Soluble epoxide hydrolase, Epoxide hydratase, Cytosolic epoxide hydrolase, SEH, CEH

Reference Data

• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways