Catalase (CAT) Rabbit Polyclonal Antibody

CAT#: AP20209PU-N

Catalase (CAT) rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry Analysis: AP20209PU-N Catalase antibody staining of Paraffin-Embedded Human brain tissue.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody antibody detects endogenous levels of Catalase protein.
• Formulation: Phosphate buffered saline (PBS), pH~7.2 containing 0.05% Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens catalase (CAT)
• Database Link:
  Entrez Gene 12359 MouseEntrez Gene 24248 RatEntrez Gene 847 Human
• Background: Catalase is a peroxisome specific marker protein belonging to the catalase family. Defects in the gene encoding for the catalase protein, CAT, can cause acatalasi,a a disease characterized by the absence of catalase activity in red cells and associated with ulcerating oral lesions. Catalase is also an important regulator of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis. Catalase, which can form a homotetramer, is found in nearly all aerobically respiring organisms and functions in protecting cells from the toxic effects of hydrogen peroxide.
• Synonyms: CAT, Peroxisome Marker

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Metabolic pathways, Methane metabolism, Tryptophan metabolism