Ephrin B1 (EFNB1) Rabbit Polyclonal Antibody

CAT#: AP20226PU-N

Ephrin B1 (EFNB1) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Ephrin-B1 antibody (AP20226PU-N) in extracts from COS7 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Ephrin-B1 protein.
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, purity is > 95% (by SDS-PAGE)
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: ~ 38 kDa
• Gene Name: Homo sapiens ephrin-B1 (EFNB1)
• Database Link:
  Entrez Gene 13641 MouseEntrez Gene 25186 RatEntrez Gene 1947 Human
• Background: Ephrins are the ligands which bind to the Eph receptor subfamily, the largest group of the receptor tyrosine kinase family. Both ephrins and Eph receptors are broadly expressed through the ectoderm, mesoderm, and endoderm of vertebrate embryos. Two classes of ephrins exist: Class A ephrins are tethered to the membrane by a GPI linkage and bind primarily to EphA receptors; Class B ephrins contain a membrane-spanning region and bind predominantly to EphB receptors. Ephrin B1 may play a role in constraining the orientation of longitudinally projecting axons.
• Synonyms: EFL-3, EFNB1, EFL3, EPLG2, LERK2, ELK-L, LERK-2, CEK5-L

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance