IL9R Rabbit Polyclonal Antibody

CAT#: AP20250PU-N

IL9R rabbit polyclonal antibody, Aff - Purified


USD 370.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC
Recommended Dilution Immunohistochemistry on paraffin sections: 1/50 - 1/200.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Specificity This antibody detects endogenous levels of IL-9R protein.
Formulation Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
Gene Name Homo sapiens interleukin 9 receptor (IL9R), transcript variant 1
Background Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.
Synonyms Interleukin-9 receptor, IL-9R, IL-9 receptor
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.